Papers on genomic stability
484 papers20 new in 30 days
Monday, April 3
Thursday, March 30
International Journal of Molecular Sciences
Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response
Experiments in cellsCellular senescence
Thursday, March 9
Biochemical Society Transactions
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling
Tuesday, March 7
Nature Communications
Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans
Experiments in wormsMechanisms
Sunday, February 26
Saturday, January 28
PLOS Genetics
Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence
Experiments in mouse cellsDNA damage response
Thursday, January 5
Tuesday, January 3
Food & Function
Effects of dietary restriction on genome stability are sex and feeding regimen dependent
Experiments in miceDietary restriction
Saturday, November 12
International Journal of Molecular Sciences
Pathological Nuclear Hallmarks in Dentate Granule Cells of Alzheimer's Patients: A Biphasic Regulation of Neurogenesis
Cross-sectional study in peopleCell cycle regulation
Friday, November 11
Gene
Pold4 is dispensable for mouse development, DNA replication and DNA repair
Experiments in miceDNA repair
Tuesday, October 11
The EMBO Journal
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Genetic association study of 550 peopleSIRT6
Saturday, September 24
Saturday, September 10
Pflugers Archiv
Exercise regulates shelterin genes and microRNAs implicated in ageing in Thoroughbred horses
Experiments in horsesExercise
Cells
Actin-Related Protein 4 and Linker Histone Sustain Yeast Replicative Ageing
Experiments in yeastMechanisms
Wednesday, August 24
medRxiv
Common genetic variations in telomere length genes and lung cancer
Preprint: Mendelian randomization in 464,716 peopleTelomerase and telomere maintenance
Tuesday, August 9
Thursday, August 4
Saturday, July 30
Frontiers in Physiology
Potential Roles of PTEN on Longevity in Two Closely Related Argopecten Scallops With Distinct Lifespans
Experiments in model organismsPTEN
Friday, July 22
Coronary Artery Disease
Identification of protective biologic factors in patients with high cardiovascular risk, but normal coronary arteries (NormCorn)
Cohort study in peopleBiomarkers
bioRxiv
Molecular Underpinnings and Environmental Drivers of Spontaneous Loss of Heterozygosity in Drosophila Intestinal Stem Cells
Preprint: experiments in fliesGut and microbiome
Tuesday, July 12
Critical Reviews in Food Science and Nutrition
Molecular bases for the use of functional foods in the management of healthy aging: Berries, curcumin, virgin olive oil and honey; three realities and a promise
ReviewCurcumin
Tuesday, June 7
FASEB BioAdvances
The roles of HMGB1-produced DNA gaps in DNA protection and aging biomarker reversal
Experiments in yeastInterventions
Wednesday, June 1
Frontiers in Endocrinology
Small Noncoding RNAome Changes During Human Bone Marrow Mesenchymal Stem Cells Senescence In Vitro
Experiments in human cellsCellular senescence
Tuesday, May 17
The Journal of Biological Chemistry
Fueling genome maintenance: On the versatile roles of NAD⁺ in preserving DNA integrity
ReviewMechanisms
Wednesday, May 4
Tuesday, May 3
Journal of Oncology
Somatic Alteration Characteristics of Early-Onset Gastric Cancer
Cross-sectional study of 1,688 peopleMechanisms
Saturday, April 16
Thursday, April 14
Cell Metabolism
SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity
Experiments in animalsCellular senescence
Wednesday, April 6
Research Square
EPAS1 protects fibroblasts from replicative senescence through telomeric stability
Preprint: experiments in miceTelomerase and telomere maintenance
Tuesday, March 29
Oxidative Medicine and Cellular Longevity
Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
ReviewInterventions