bioRxiv
Brief enzyme inhibition enhances reprogramming in human cells
Experiments in human blood cells found that briefly inhibiting a DNA-copying enzyme enhanced their conversion into stem cells while preserving genetic stability.Experiments in human blood cells found that briefly inhibiting a DNA-copying enzyme enhanced their conversion into stem cells while preserving genetic stability.
Preprint: human cell studyInterventions
Who was studiedHuman peripheral blood mononuclear cells
What changedTransient inhibition of DNA polymerase alpha enhanced reprogramming of human blood cells into stem cells
The catchWhether reprogramming slows aging was not measured