GCIPL thickness is associated with cortical atrophy in humans.
“GCIPL thickness and SVC density were associated with cortical atrophy in AD-vulnerable regions, including temporal, parietal, and occipital cortices.”
HumansAlzheimer's diseasetemporal, parietal, and occipital cortices
A cross-sectional study of 181 people linked retinal changes to brain shrinkage, blood markers of Alzheimer's disease and cognitive impairment.A cross-sectional study of 181 people linked retinal changes to brain shrinkage, blood markers of Alzheimer's disease and cognitive impairment.
What changedThinner retinal nerve-cell layers and lower retinal blood-vessel density were linked to more brain shrinkage in people with Alzheimer's disease
The catchSystemic vascular health could partly explain the link between retinal changes and brain shrinkage
Thicker retinal nerve fiber layers were linked to lower cardiovascular event rates in 51,293 participants, with an adjusted hazard ratio of 0.92.Thicker retinal nerve fiber layers were linked to lower cardiovascular event rates in 51,293 participants, with an adjusted hazard ratio of 0.92.
Who was studied49,787 UK Biobank adults without prior cardiovascular events, median 14.6 years
What changedThicker retinal nerve fiber layers were linked to lower cardiovascular event risk (adjusted hazard ratio 0.92 per standard-deviation increase)
The catchAssociations with ischemic and hemorrhagic stroke were not analyzed separately
Adults missing 22–28 teeth had 1.92 times the odds of glaucoma compared with those missing none in a population-based observational study.Adults missing 22–28 teeth had 1.92 times the odds of glaucoma compared with those missing none in a population-based observational study.