Amyloid-β PET positivity

1. Plasma Aβ42/40 combined with P-TAU231 or P-TAU181 predicts amyloid-β PET positivity in humans (AUC range 0.81–0.86).

   “Combining Aβ42/40 with p-tau231 or p-tau181 allowed for good distinction between Aβ-negative and -positive participants”

   Humanscognitively unimpaired; family history of AD dementian = 129

   Plasma p-tau231, p-tau181, PET Biomarkers, and Cognitive Change in Older Adults

   Annals of neurology·18 Feb 2022

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