FoxM1 expression

Biomarker

3 papers3 findings

  • Humans1
  • Animals1
  • Cells1

Interventions

2

Dydrogesterone

upin human cells1

1 study
  1. Dydrogesterone increases FoxM1 expression in human cells.

    “MPA and DYD restored FOXM1 expression and improved decidual function, but did not reverse senescence marker expression.”

    CellsCells from women with recurrent pregnancy lossdecidual cellfemales

    Decidual senescence in recurrent pregnancy loss: forkhead box M1-targeted progesterone treatment

    Reproductive biomedicine online28 Feb 2026

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Medroxyprogesterone acetate

upin human cells1

1 study
  1. Medroxyprogesterone acetate increases FoxM1 expression in human cells.

    “MPA and DYD restored FOXM1 expression and improved decidual function, but did not reverse senescence marker expression.”

    CellsCells from women with recurrent pregnancy lossdecidual cellfemales

    Decidual senescence in recurrent pregnancy loss: forkhead box M1-targeted progesterone treatment

    Reproductive biomedicine online28 Feb 2026

More on Medroxyprogesterone acetate

Upstream

1

TP53

downin human cells1

1 study
  1. TP53 decreases FoxM1 expression in human cells.

    “MiP-FERMT3 also promoted the nuclear accumulation of p53, which subsequently repressed FOXM1 expression”

    CellsmiP-FERMT3 overexpressionendothelial cell

    A microprotein encoded by FERMT3 modulates endothelial cell protein catabolism and induces p53-mediated cell cycle arrest and senescence

    bioRxiv (Cold Spring Harbor Laboratory)3 Dec 2025Preprint

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