Biochemical and Biophysical Research Communications·Apr 20Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosisExperiments in miceCellular senescencePaper
Aging and Disease·Apr 5Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant ResponseExperiments in miceInterventionsPaper
Journal of Periodontology·Apr 2Periodontitis and cognitive impairment in older adults: The mediating role of mitochondrial dysfunctionCross-sectional study of 1,883 peopleMitochondrionPaper
Open Heart·Mar 19Ferulic acid and berberine, via Sirt1 and AMPK, may act as cell cleansing promoters of healthy longevityReviewBerberinePaper
The Journals of Gerontology, Series A·Mar 13Chlorogenic Acid Activates Nrf2/SKN-1 and Prolongs the Lifespan of Caenorhabditis elegans via the Akt-FOXO3/DAF16a-DDB1 Pathway and Activation of DAF16fExperiments in wormsInterventionsPaper
Oxidative Medicine and Cellular Longevity·Mar 1Nrf2 Deficiency Attenuates Testosterone Efficiency in Ameliorating Mitochondrial Function of the Substantia Nigra in Aged Male MiceExperiments in miceTestosteronePaper
Clinical and Translational Medicine·Feb 28Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2-mediated chromatin remodellingStudy in peopleMelatoninPaper
European Journal of Pharmacology·Feb 26Urolithin A attenuates RANKL-induced osteoclastogenesis by co-regulating the p38 MAPK and Nrf2 signaling pathwayExperiments in miceUrolithin APaper
Autophagy·Feb 20Loss of ubiquitinated protein autophagy is compensated by persistent cnc/NFE2L2/Nrf2 antioxidant responsesExperiments in fliesNRF2–KEAP1 antioxidant responsePaper
Redox Biology·Feb 8REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2Experiments in miceNRF2–KEAP1 antioxidant responsePaper
Biomedicine & Pharmacotherapy·Feb 2Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1/Nrf2/HO-1 pathwayExperiments in human cellsNicotinamide mononucleotidePaper
Experimental Gerontology·Feb 2Factor analysis to determine relative contributions of strength, physical performance, body composition and muscle mass to disability and mobility disability outcomes in older menCohort study of 1,345 peopleGrip strengthPaper
Circulation·Jan 31Salt-Induced Hepatic Inflammatory Memory Contributes to Cardiovascular Damage Through Epigenetic Modulation of SIRT3Experiments in miceCardiovascular diseasePaper
Current Molecular Pharmacology·Jan 29Humanin Ameliorates Late-onset Hypogonadism in Aged Male RatsExperiments in 40 ratsInterventionsPaper
Preprints.org·Jan 27Social and Emotional Loneliness among Older People Living in Nursing Homes in Spain: A Cross-Sectional StudyPreprint: cross-sectional study of 65 peoplePopulationsPaper
Molecular Neurobiology·Jan 7Lipopolysaccharide Induces Gliotoxicity in Hippocampal Astrocytes from Aged Rats: Insights About the Glioprotective Roles of ResveratrolExperiments in ratsResveratrolPaper
BMC Bioinformatics·Jan 6Machine learning-based predictions of dietary restriction associations across ageing-related genesComputational studyMachine learningPaper
Nutrients·Dec 29The Association between 25-Hydroxyvitamin D Concentration and Telomere Length in the Very-Old: The Newcastle 85+ StudyCohort study of 775 people25-hydroxyvitamin DPaper
Antioxidants·Dec 25The KEAP1-NRF2 System in Healthy Aging and LongevityReviewNRF2–KEAP1 antioxidant responsePaper
Innovation in Aging·Dec 17Examining the Relationship Between Preference for Solitude and Subjective Well-Being Among Japanese Older AdultsCross-sectional study of 276 peoplePopulationsPaper
Biochemical Society Transactions·Dec 17Translational control in cell ageing: an updateReviewMechanismsPaper
Frontiers in Endocrinology·Dec 14The Polymorphism at PLCB4 Promoter (rs6086746) Changes the Binding Affinity of RUNX2 and Affects Osteoporosis Susceptibility: An Analysis of Bioinformatics-Based Case-Control Study and Functional ValidationStudy in peopleMechanismsPaper
Frontiers in Pharmacology·Dec 14Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 SignalingExperiments in animalsInterventionsPaper
Aging·Dec 3Licochalcone A activation of glycolysis pathway has an anti-aging effect on human adipose stem cellsExperiments in human cellsInterventionsPaper
Cardiovascular Engineering and Technology·Dec 2The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the Inflammatory Response of H9c2 Cells Through the Nrf2/ARE and NF-κB PathwaysExperiments in rat cellsInterventionsPaper
Alternative Therapies in Health and Medicine·Dec 1Acupuncture Attenuates Ototoxicity Induced by Gentamicin in MiceExperiments in animalsInterventionsPaper
Free Radical Biology & Medicine·Nov 26Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fissionExperiments in miceExercisePaper
Aging·Nov 24Atorvastatin combined with dexamethasone promote hematoma absorption in an optimized rat model of chronic subdural hematomaExperiments in ratsStatinsPaper
Frontiers in Oncology·Nov 23TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic CancerExperiments in human cellsCellular senescencePaper
The Journal of Nutritional Biochemistry·Nov 22N-3 PUFA ameliorated bone loss induced by postmenopausal depression following exposure to chronic mild stress and maternal separation by regulating neuronal processesExperiments in animalsInterventionsPaper