Expression of genes related to neurogenesis and response to mechanical stimulus

1. Pdgf-ab/bb decreases expression of genes related to neurogenesis and response to mechanical stimulus in human cells.

   “PDGF-AB/BB treatment resulted in downregulation of gene clusters related to neurogenesis and response to mechanical stimulus in AF cells”

   Cellsderived from degenerated intervertebral discsrecombinant humanannulus fibrosus cell5 days

   Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc

   eLife·2 Jun 2025Preprint

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