1 paper2 findings
Tauopathies
downin mice1
Tauopathies decrease ectopic lymphoid structures in mice.
“Tauopathy and DS models showed significantly fewer ELS than controls.”
AnimalsK257T/P301S tauopathy and Dp1Tyb Down syndrome micecranial dural meninges
AAIC 2025 abstract23 Dec 2025
Early-onset Alzheimer's disease
upin mice1
Early-onset Alzheimer's disease increases ectopic lymphoid structures in mice.
“In 5xFAD mice, ELS formation intensified with pathology”
Animals5xFAD micecranial dural meninges
AAIC 2025 abstract23 Dec 2025
Keeping immune cells in mouse tissues or increasing their numbers produced clusters across several organs without associated signs of disease.Keeping immune cells in mouse tissues or increasing their numbers produced clusters across several organs without associated signs of disease.