Docosahexaenoate

Biomarker

1 paper

  • Animals1

Latest

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Molecular Biomedicine

Dietary fat rebalanced brain membrane fats in mice

Docosahexaenoic acid restored brain energy function in six- and 12-month dietary experiments in female mice carrying a human gene variant linked to Alzheimer’s disease.Docosahexaenoic acid restored brain energy function in six- and 12-month dietary experiments in female mice carrying a human gene variant linked to Alzheimer’s disease.

Experiments in 37 female ApoE3/3 and ApoE4/4 knock-in mice, against control-diet ApoE4/4 miceInterventions

Limit: Lipidomics sampled cerebellum, not cortex or hippocampus, limiting claims about brain-wide membrane rebalancing

Clinical Nutrition ESPEN

Higher blood omega-3 levels linked to lower risk of death

Mexican adults with the highest levels of non-DHA omega-3 fats had a 20% lower hazard of death than those with the lowest.Mexican adults with the highest levels of non-DHA omega-3 fats had a 20% lower hazard of death than those with the lowest.

Cohort study of 144,900 peoplePopulations
European Journal of Nutrition

Blood chemistry partly explained diet’s link to waist size

The share of blood fatty acids that were polyunsaturated partly accounted for the diet–waist link: 35.6% in men and 46.5% in women.The share of blood fatty acids that were polyunsaturated partly accounted for the diet–waist link: 35.6% in men and 46.5% in women.

Cohort study of 10,242 peopleMechanisms