Dendritic spines

Biomarker

2 papers1 finding

  • Animals2

Interventions

1

Digoxin

upin mice1

1 study
  1. Digoxin increases dendritic spines in mice.

    “demonstrated a selective increase in filopodia and thin-type dendritic spines, which are associated with structural remodeling”

    Animalsmotor cortex

    Low-Dose Digoxin Ameliorates Age-Related Motor Learning Deficits in Mice

    Neurochemical research8 Sep 2026

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bioRxiv

App knock-in mice display age-dependent Alzheimer's pathology

In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.

Preprint: experiments in miceAPP