Cytokine secretion

Biomarker

7 papers study it172 more mention it1 finding

Humans1
Animals3
Cells2

Interventions

Proteasome inhibition

upin mouse cells1

1 study

Proteasome inhibition increases cytokine secretion in mouse cells (13 of 62 analyzed cytokines increased).
“while SIPS and RS showed an increase in the secretion of most cytokines, and in PIIPS only 13 were incremented.”
Cellsproteasome inhibition-induced premature senescenceprimary lung fibroblasts
Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli
Age (Dordrecht, Netherlands)Feb 11, 2016

Latest

31 papers in 12 months

Journal of Translational MedicineOct 14

Some T cell responses were weaker in older COVID-19 survivors

An observational study of COVID-19 survivors aged 18–59 and 60 or older found weaker responses after inactivated vaccines and subsequent Omicron infection in older…An observational study of COVID-19 survivors aged 18–59 and 60 or older found weaker responses after inactivated vaccines and subsequent Omicron infection in older adults.

Cohort studyImmune response

Paper

Skin Research and TechnologyOct 12

Effect of Dermal Fibroblast-Conditioned Media on Human Dermal Fibroblasts Treated With Electromagnetic Transduction Therapy

Experiments in human cellsInterventions

Paper

bioRxivOct 2

The hydrocup: a hollow electrospun scaffold for in vivo hydrogel-laden cell delivery

Preprint: experiments in ratsInterventions

Paper

Bulletin of Experimental Biology and MedicineSep 29

NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages

Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.

Experiments in cellsNLRP3 inflammasome

Paper

Connective Tissue ResearchSep 23