Cortical thinning

Biomarker

2 papers

  • Humans1
  • In silico1

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Journal of Neurology

Brain thinning detected before dementia in people under 65

An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.An observational study of 292 people under 65 linked two positive Alzheimer’s-related spinal-fluid tests to earlier and more extensive thinning.

Cross-sectional study of 292 peopleDementia
Human Brain Mapping

White matter damage is linked to greater cortical thinning in men

In 104 older adults followed for nine years, white matter aberrations grew 7.2% annually, tracking greater cortical thinning and expanded cortical area in men.In 104 older adults followed for nine years, white matter aberrations grew 7.2% annually, tracking greater cortical thinning and expanded cortical area in men.

Cohort study of 104 peoplePopulations
Alzheimer's & Dementia

WTC neurotoxicant exposure links to cortical thinning

In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.

Cross-sectional study of 218 peoplePopulations