Pure-tone average

1. Waist circumference is associated with pure-tone average in humans (+1.57 dB HL per 10 cm (95% CI, 0.74 to 2.39)).

   “Waist circumference alone met the nine-test Holm criterion: +1.57 dB HL per 10 cm (95% CI, 0.74 to 2.39; Holm p = 0.00547).”

   Humansn = 778

   When CKM Syndrome Stage Is Not a Severity Scale: Audiometric Hearing Thresholds in Older U.S. Adults · medRxiv · 17 Sep 2026 · Preprint

Waist circumference →

1. Pioglitazone is associated with pure-tone average in humans.

   Humansin patients with T2DM

   Associations Between Antidiabetic Pharmacotherapy and Hearing Thresholds in Adult Hearing-Impaired Patients With Type 2 Diabetes · Pharmacology research & perspectives · 10 Sep 2026

Pioglitazone →

1. Metformin is associated with pure-tone average in humans.

   Humansin patients with T2DM

   Associations Between Antidiabetic Pharmacotherapy and Hearing Thresholds in Adult Hearing-Impaired Patients With Type 2 Diabetes · Pharmacology research & perspectives · 10 Sep 2026

Metformin →

1. GLP-1 receptor agonists are associated with pure-tone average in humans.

   Humansin patients with T2DM

   Associations Between Antidiabetic Pharmacotherapy and Hearing Thresholds in Adult Hearing-Impaired Patients With Type 2 Diabetes · Pharmacology research & perspectives · 10 Sep 2026

GLP-1 receptor agonists →

1. Saturated fatty acids are associated with pure-tone average in humans (β = -1.704 dB HL; 95% CI, -2.872 to -0.536).

   HumansQ4 vs. Q1males

   Seafood and polyunsaturated fatty acid intake and age-related hearing loss: a cross-sectional study conducted in Japan · The journal of nutrition, health & aging · 4 Sep 2026

Saturated fatty acids →

1. AHHIA-S score is associated with pure-tone average in humans (rho = 0.71, p < 0.001).

   Humansin Arabic-speaking adultsn = 60

   Cross-cultural adaptation and psychometric determining of the Arabic version of the Hearing Handicap Inventory forAdults-Screening version (AHHIA-S) · Research Square · 26 Aug 2026 · Preprint