What does the research say about constipation?

Constipation

There are 3 papers on constipation in aging research: 1 observational study in people, 2 reviews. The newest story, Nov 10, 2026: “Constipation-linked death rates rose in the United States”.

Biomarker

3 papers study it328 more mention it

19 new papers in 30 daysSee all 331 papers on constipation

Humans1

Latest

107 papers in 12 months

Preprints.orgNov 14

Nutritional Strategies for Managing Gastrointestinal Adverse Effects Associated with GLP-1 Receptor Agonist and Dual GIP/GLP-1 Receptor Agonist Therapy: A Narrative Review with Practical Recommendations

Preprint: reviewGLP-1 receptor agonists

Paper

The Lancet Gastroenterology & HepatologyNov 12

Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 48-week results from a multicentre, randomised, double-blind, phase 2b study

Randomized trial in 212 peopleMetabolic dysfunction-associated steatohepatitis

Paper

Research SquareNov 11

An index of oral-type gut genera is associated with lower muscle mass and with 3- year muscle loss in community-dwelling older adults: a cohort study

Preprint: cohort study of 782 peopleMuscle

Paper

Research SquareNov 11

Safety and efficacy of oral non-peptide GLP-1 receptor agonist in non- diabetic obese patients; systematic review and meta-analysis of randomized controlled trials

Preprint: meta-analysis of randomized trialsGLP-1 receptor agonists

Paper

CureusNov 11

Efficacy and Safety of Oral Orforglipron for Weight Reduction in Adults With Overweight or Obesity: A Systematic Review

Systematic review of randomized trialsOrforglipron

Paper

European Journal of Case Reports in Internal MedicineNov 11

Iatrogenic Hypercalcemia in A Patient with Type 2 Diabetes and Chronic Kidney Disease

Case reportChronic kidney disease

Paper

European Journal of Obstetrics, Gynecology, and Reproductive BiologyNov 11

Polypharmacy and the ageing brain: Anticholinergic burden in the ageing population and the impact of gynaecological medications

ReviewPolypharmacy

Paper

BMC GastroenterologyNov 10

Constipation-linked death rates rose in the United States

Death rates adjusted for age rose from 0.26 in 1999 to 0.55 in 2024, with faster increases among men.Death rates adjusted for age rose from 0.26 in 1999 to 0.55 in 2024, with faster increases among men.

Cross-sectional · 22,237 peopleConstipation