C1q
Biomarker2 papers3 findings
- Human trial1
- Humans1
Associations
3NfL
upin humans1
1 study
NfL
upin humans1
C1q is associated with NfL in humans.
Humansacross cognitively normal, MCI, and dementia stages of ADcerebrospinal fluid
CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer's disease · bioRxiv · 27 Aug 2026 · Preprint
Cognitive function
downin humans1
1 study
Cognitive function
downin humans1
C1q is associated with cognitive function in humans.
Humansin cognitively unimpaired individuals at increased familial risk of ADcerebrospinal fluid
CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer's disease · bioRxiv · 27 Aug 2026 · Preprint
P-TAU181
upin humans1
1 study
P-TAU181
upin humans1
C1q is associated with P-TAU181 in humans.
Humansin cognitively unimpaired individuals at increased familial risk of ADcerebrospinal fluid
CSF complement proteins are associated with early tau pathology and synaptic damage in an asymptomatic population at risk of Alzheimer's disease · bioRxiv · 27 Aug 2026 · Preprint