Circulating progenitor cells

1. Atherosclerotic cardiovascular disease increases circulating progenitor cells in humans.

   “Despite an increased number of circulating precursors in ASCVD patients, ASCVD impaired the colony forming capacity and the angiogenic properties of ECFC in a severity-dependent manner.”

   Humansin ASCVD patients

   Functional Impairment of Endothelial Colony Forming Cells (ECFC) in Patients with Severe Atherosclerotic Cardiovascular Disease (ASCVD)

   International journal of molecular sciences·Aug 11, 2022

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1. Circulating progenitor cells predict vascular dysfunction in humans.

   “A lower CPC count at baseline was an independent predictor of worsening vascular function during 2-year follow-up.”

   Humans2-year follow-up

   The association between baseline circulating progenitor cells and vascular function: The role of aging and risk factors

   Vascular medicine (London, England)·Sep 5, 2022

1. Circulating progenitor cells are associated with reactive hyperemia index in humans.

   “Among younger subjects (< 48 years), CPC counts were higher in those with risk factors and vascular function was better in those with higher compared to those with lower CPC counts”

   Humanspresence of risk factors

   The association between baseline circulating progenitor cells and vascular function: The role of aging and risk factors

   Vascular medicine (London, England)·Sep 5, 2022

More on Reactive hyperemia index