Papers on cerebral microhemorrhages

22 papers1 new in 30 days

Tuesday, October 20

The Journal of Prevention of Alzheimer's DiseaseOct 20

Cerebral microhemorrhage and cognition in preclinical Alzheimer's disease

Cohort study in peoplePreclinical Alzheimer's disease

Paper

Wednesday, September 9

Alzheimer's & DementiaSep 9

MCH-Guard: Multimodal machine learning framework for risk stratification of cerebral microhemorrhage risk in the Alzheimer's Disease Neuroimaging Initiative

Cross‐sectional prediction of microhemorrhage (MCH) presence (classification models).

Computational studyBiomarkers

Paper

Thursday, January 8

AAIC 2025 AbstractJan 8

Age‐associated changes in neuroimaging biomarkers in a non‐human primate model of cerebral amyloid angiopathy

Experiments in animalsCerebral amyloid angiopathy

Paper

Friday, September 26

Scientific ReportsSep 26

Gut dysbiosis and brain microhemorrhages in young vs. aged mice with chronic kidney disease

Experiments in miceMicrobiome composition

Paper

Wednesday, August 20

Alzheimer's & DementiaAug 20

Prevalence and risk factors of cerebral microhemorrhages and superficial siderosis in cognitively unimpaired older adults: analysis from the CHARIOT-PRO SubStudy

Cross-sectional study of 1,414 peopleBiomarkers

Paper

Friday, April 11

GeroScienceApr 11

Clonal hematopoiesis of indeterminate potential (CHIP) in cerebromicrovascular aging: implications for vascular contributions to cognitive impairment and dementia (VCID)

ReviewBlood and immune system

Paper

Wednesday, April 2

GeroScienceApr 2

Aging, mitochondrial dysfunction, and cerebral microhemorrhages: a preclinical evaluation of SS-31 (elamipretide) and development of a high-throughput machine learning-driven imaging pipeline for cerebromicrovascular protection therapeutic screening

Experiments in miceInterventions

Paper

Friday, March 21

GeroScienceMar 21

Cerebromicrovascular senescence in vascular cognitive impairment: does accelerated microvascular aging accompany atherosclerosis?

ReviewCellular senescence

Paper

Thursday, October 17

medRxivOct 17

Plasma proteome-wide analysis of cerebral small vessel disease identifies novel biomarkers and disease pathways

Preprint: cohort study of 1,508 peopleCerebral small vessel disease

Paper

Saturday, September 14

GeroScienceSep 14

The vasoprotective role of IGF-1 signaling in the cerebral microcirculation: prevention of cerebral microhemorrhages in aging

ReviewInsulin/IGF-1 signaling

Paper

Friday, April 19

GeroScienceApr 19

Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages

ReviewMechanisms

Paper

Monday, December 4

GeroScienceDec 4

Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax

Experiments in miceNavitoclax

Paper

Tuesday, October 19

Frontiers in Aging NeuroscienceOct 19

The Effect of Mild Traumatic Brain Injury on Cerebral Microbleeds in Aging

Cohort study in peopleMechanisms

Paper

Saturday, August 21

GeroScienceAug 21

Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice

Experiments in miceMechanisms

Paper

Wednesday, December 2

Neurobiology of AgingDec 2

Age and diet modify acute microhemorrhage outcome in the mouse brain

Experiments in animalsMechanisms

Paper

Wednesday, October 16

Frontiers in NeurologyOct 16

Effects of Dabigatran in Mouse Models of Aging and Cerebral Amyloid Angiopathy

Experiments in animalsInterventions

Paper

Saturday, March 9

American Journal of Physiology Heart and Circulatory PhysiologyMar 9

Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

ReviewMechanisms

Paper

Thursday, March 8

Journal of NeuroinflammationMar 8

Aging exacerbates development of cerebral microbleeds in a mouse model

Experiments in animalsMechanisms

Paper

Thursday, August 31

GeroScienceAug 31

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease

ReviewMechanisms

Paper

Tuesday, March 21

American Journal of Physiology Heart and Circulatory PhysiologyMar 21

Cerebral microhemorrhages: mechanisms, consequences, and prevention

ReviewMechanisms

Paper

Sunday, October 30

American Journal of Physiology Heart and Circulatory PhysiologyOct 30

Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

ReviewMechanisms

Paper

Wednesday, June 26

Journal of Cerebral Blood Flow and MetabolismJun 26

Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease

Experiments in miceRapamycin

Paper