Cell proliferation rate

5 papers2 findings

Animals4
Cells1

Interventions

1

Methionine restriction

downin mice1

1 study

Methionine restriction decreases cell proliferation rate in mice (46-64% (P < 0.02)).
“The reduction in PIN severity was associated with 46-64% reductions in cell proliferation rates (P < 0.02)”
Animalsin TRAMP mice0.12% Met
Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice
The Prostate22 Sep 2014

More on Methionine restriction

Upstream

1

FGF21

downin mice1

1 study

FGF21 decreases cell proliferation rate in mice.
“compared to AL-fed WT mice, AL-fed FGF21-knockout mice exhibited higher basal rates of cell proliferation”
AnimalsAL-fed mice
Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice
PloS one4 Nov 2014

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3 in 12 months

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Experiments in human cellsSenescence-associated secretory phenotype (SASP)

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Acute and Lifelong Exercise Modulate the Tumorigenic Potential of Human Lung Cancer Cells and Their Susceptibility to Cisplatin

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Exposure to polystyrene nanoplastics promotes premature cellular senescence through mitochondrial ROS production and dysfunction in pre-differentiated skeletal myoblasts

Experiments in cellsMechanisms

Bio Systems17 Mar

Unraveling power-law scaling through exponential cell division dynamics

Computational studyMechanisms

Journal of Dental Sciences2 Feb

Quercetin ameliorates advanced glycation end product-induced wound healing impairment and inflammaging in human gingival fibroblasts

Experiments in human cellsQuercetin

Aging Cell6 Nov

Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice

Experiments in miceInterventions

PLOS One4 Nov

Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice

Experiments in miceMechanisms

The Prostate22 Sep

Dietary methionine restriction inhibits prostatic intraepithelial neoplasia in TRAMP mice

Experiments in miceDietary restriction