CD4 T cell senescence

Biomarker

3 papers study it17 more mention it1 finding

Humans2
Animals1

Associations

CSF-infiltrating CD28+ CD27-EM CD4+ T cells

upin humans1

1 study

CD4 T cell senescence is associated with CSF-infiltrating CD28+ CD27-EM CD4+ T cells in humans.
“Patients with high levels of CD4+ T-cell senescence in peripheral blood showed increased frequencies of CSF-infiltrating CD28+ CD27-EM CD4+ T cells”
Humansin patients with MScerebrospinal fluid
Characterization of Antigen-Induced CD4+ T-Cell Senescence in Multiple Sclerosis
Frontiers in neurologyFeb 3, 2022

Funding

1 grant since 2026

Natural Science Foundation of Hunan Province

Molecular mechanism of Treponema pallidum outer membrane protein Tp92 regulating MYC via host membrane protein interactions to induce CD4⁺ T cell senescence
Natural Science Foundation of Hunan ProvinceUniversity of South China2026

Latest

6 papers in 12 months

NPJ AgingOct 14

Lactate worsened arthritis and bone erosion in animals

In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.

Animal studyBones and joints