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CD8+ T-cell co-stimulation and senescence

Biomarker

1 paper studies it2 findings

  • Humans1

Effects

2

Depressive symptoms

upin humans1

1 study

  1. CD8+ T-cell co-stimulation and senescence increases depressive symptoms in humans (P < 0.05).

    “CD8+ T-cell co-stimulation and senescence was associated with higher depression (P's < 0.05).”

    Humansin virally suppressed women with HIVfemales

    T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV

    Brain, behavior, & immunity - health

Executive function

downin humans1

1 study

  1. CD8+ T-cell co-stimulation and senescence impairs executive function in humans (P < 0.05).

    “CD8+ T-cell co-stimulation and senescence was associated with poorer executive function (P's < 0.05).”

    Humansin women with HIVfemalesn = 369

    T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV

    Brain, behavior, & immunity - health

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