Carotid-artery intima-media thickness

1. MOG is associated with carotid-artery intima-media thickness in humans.

   “In meta‐analysis (both groups), QDPR|P09417 and MOG|Q16653 (myelin sheath) were associated with higher mean carotid IMT.”

   Humansin meta-analysis (both groups)cerebrospinal fluid

   Cerebrospinal Fluid Proteins as Biomarkers of Brain Vascular Injury

   AAIC 2025 abstract·9 Jan 2026

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1. PLP1 is associated with carotid-artery intima-media thickness in humans.

   “For AA participants, PLP1|P60201 (myelin sheath) was associated with higher IMT.”

   Humansfor AA participantscerebrospinal fluid

   Cerebrospinal Fluid Proteins as Biomarkers of Brain Vascular Injury

   AAIC 2025 abstract·9 Jan 2026

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1. QDPR is associated with carotid-artery intima-media thickness in humans.

   “Among white participants, QDPR|P09417 (neurotransmitter production) was associated with higher IMT.”

   Humansin white participantscerebrospinal fluid

   Cerebrospinal Fluid Proteins as Biomarkers of Brain Vascular Injury

   AAIC 2025 abstract·9 Jan 2026

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1. Luteinizing hormone is associated with carotid-artery intima-media thickness in humans (p = 0.006).

   “and directly with LH (p = 0.006) in multivariate models adjusted for age, total cholesterol, body mass index, blood pressure, and smoking.”

   Humansadjusted for age, total cholesterol, BMI, blood pressure, smokingcarotid arterymales

   Increased carotid atherosclerosis in andropausal middle-aged men

   Journal of the American College of Cardiology·17 May 2005

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1. Testosterone is associated with carotid-artery intima-media thickness in humans (p = 0.003).

   “Common carotid IMT correlated inversely with serum testosterone (p = 0.003)”

   Humansadjusted for age, total cholesterol, BMI, blood pressure, smokingcarotid arterymales

   Increased carotid atherosclerosis in andropausal middle-aged men

   Journal of the American College of Cardiology·17 May 2005

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1. Andropause is associated with carotid-artery intima-media thickness in humans (1.08 +/- 0.34 vs. 1.00 +/- 0.23, p < 0.05).

   “Andropausal men had a higher maximal IMT compared with controls in the common carotid (1.08 +/- 0.34 vs. 1.00 +/- 0.23, p < 0.05)”

   Humansandropausal men vs controlscarotid arterymales

   Increased carotid atherosclerosis in andropausal middle-aged men

   Journal of the American College of Cardiology·17 May 2005

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