European Journal of Pharmacology
Gut microbe products helped metformin protect bone in mice
Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.Experiments in mice with ovaries removed linked the drug’s bone benefits to short-chain fatty acids, small molecules made by gut bacteria.
Experiments in mice with ovaries removedMetformin
Limit: Metformin doses were not reported, preventing assessment of the exposure required for bone protection