Brain imaging‐derived phenotypes
4 papers study it1 more mentions it1 finding
- Humans4
Associations
1Fine particulate matter
mixedin humans1
1 study
Fine particulate matter
mixedin humans1
Fine particulate matter is associated with brain imaging‐derived phenotypes in humans (6 significant interactions, p < 0.05).
“We identified six significant PGS‐by‐environment interactions between PM 2.5 and AD polygenic score ( p < 0.05 ) in both regional volumes and white matter tracts”
Humansinteraction with Alzheimer's disease polygenic scorebrainn = 47,258
AAIC 2025 abstractDec 24, 2025
Latest
1 paper in 12 monthsAAIC 2025 Abstract
Genome‐Wide by Environment Interaction Studies of PM 2.5 and Alzheheimer's Genetic Risk Across Brain Imaging Phenotypes in UK Biobank
Genetic association study of 47,258 peoplePopulations
Cerebral Cortex
Exploring the neural mechanisms linking healthy aging and cognitive maintenance: insights from Mendelian randomization and mediation analyses
Mendelian randomization in peopleMechanisms
The Journal of Clinical Endocrinology and Metabolism
The Effect of SGLT2 Inhibition on Brain-related Phenotypes and Aging: A Drug Target Mendelian Randomization Study
Mendelian randomization in 389,166 peopleMechanisms
Aging Cell
Casual associations between brain structure and sarcopenia: A large-scale genetic correlation and mendelian randomization study
Mendelian randomization in peopleMuscle