Brain glucose uptake

Biomarker

1 paper1 finding

  • Human trial1

Interventions

1

Metformin

upin humans1

1 study
  1. Metformin increases brain glucose uptake in humans.

    “Increased glucose uptake in brain areas rich in insulin receptors, such as the prefrontal cortex, support that metformin enhanced insulin sensitivity”

    Human trialinsulin-resistantbrain2500 mg/d40 weeksn = 40

    Metformin Improves Brain Glucose Uptake, Network Connectivity, and Volume Concurrent to Improved Working Memory and Processing Speed in Insulin-Resistant Older Adults

    ADA Scientific Sessions 2025 abstract13 Jun 2025

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