Biological aging

Biomarker2 papers3 findings

  • Human trial1
  • Humans1

Associations

3

Mortality

upin humans1HR 1.21–2.34

1 study
  1. Biological aging raises the risk of mortality in humans (HR range 1.21-2.34).

    Humansamong individuals with gout

    Accelerated biological aging links to higher gout risk and increased mortality · Maturitas · 25 Sep 2026

Gout

upin humans1OR 1.04

1 study
  1. Biological aging raises the risk of gout in humans (OR 1.04, 95% CI 1.03-1.05).

    Humans

    Accelerated biological aging links to higher gout risk and increased mortality · Maturitas · 25 Sep 2026

Gout →

Ferritin

upin humans1

1 study
  1. Ferritin is associated with biological aging in humans (1.93 additional years).

    Humanscompared with median ferritin (47 ug/L) at WHO threshold (15 ug/L)females

    Association Between Iron Availability and Accelerated Biological Aging in Non-Anemic Women of Reproductive Age: A Nationally Representative Cross-Sectional Study · Biological trace element research · 12 Sep 2026

Ferritin →

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 5Aug 2026: 19Sep 2026: 156Oct 2026: 18199
medRxivHumansPreprint

Hormone therapy linked to lower breast cancer mortality

Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death…Compared with never-users, hormone therapy ever-users had adjusted hazard ratios, which compare event rates over time, of 0.72 for breast cancer death and 1.17 for diagnosis.

PLOS MedicineHumans

Aging index better predicted death in US adults

In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.

GeroScienceHumans

Biological aging and frailty linked to thinner central retinas

Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27%…Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.

bioRxivHumansPreprint

Blood protein clock tracks shifts in health risks over time

In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher…In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.

Clinical EpigeneticsHumans

Organ aging measures have varied genetic links to disease

An analysis using inherited genetic differences prioritised 31 of 306 assessable comparisons between organ aging measures and age-related conditions…An analysis using inherited genetic differences prioritised 31 of 306 assessable comparisons between organ aging measures and age-related conditions in European-ancestry datasets.

Clinical Gastroenterology and HepatologyHumans

Faster biological aging linked to early colorectal adenocarcinoma

In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those…In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those without it.