APP localization

1. ARF4 is associated with APP localization in mice.

   “The consequence of Arf4 knockdown was an alteration in amyloid precursor protein (APP) localization, which led to variations in mature APP levels.”

   Animalsshown by Arf4 knockdown in PSAPP/Arf4 +/− mice

   The effects of Arf4 gene knockdown on Alzheimer's amyloid β deposition: Possible role in cognitive resilience

   Research Square·14 Oct 2026Preprint

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