European Review for Medical and Pharmacological Sciences·Nov 18Metformin suppresses progression of muscle aging via activation of the AMP kinase-mediated pathways in Drosophila adultsExperiments in fliesMetforminPaper
Annals of Laboratory Medicine·Oct 26Clinical, Mutational, and Transcriptomic Characteristics in Elderly Korean Individuals With Clonal Hematopoiesis Driver MutationsCross-sectional study of 90 peopleBlood and immune systemPaper
Molecular Ecology·Oct 14Epigenetics and island-mainland divergence in an insectivorous small mammalExperiments in animalsBiomarkersPaper
bioRxiv·Sep 2CRTC-1 balances histone trimethylation and acetylation to promote longevityPreprint: experiments in wormsMechanismsPaper
Nature·Jul 6Molecular landscapes of human hippocampal immature neurons across lifespanCross-sectional study in peopleMechanismsPaper
International Reviews of Immunology·May 21Role of thymus in health and diseaseReviewBlood and immune systemPaper
The Journal of Biological Chemistry·Apr 24Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylationExperiments in miceCircadian clockPaper
eLife·Apr 8Multi-omic rejuvenation of human cells by maturation phase transient reprogrammingExperiments in human cellsInterventionsPaper
Aging·Mar 21Cell immortalization facilitates prelamin A clearance by increasing both cell proliferation and autophagic fluxExperiments in mouse cellsAutophagyPaper
Cells·Feb 26Small Extracellular Vesicles from Peripheral Blood of Aged Mice Pass the Blood-Brain Barrier and Induce Glial Cell ActivationExperiments in miceMechanismsPaper
Theranostics·Jan 4Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged miceExperiments in miceEpigenetic regulation of gene expressionPaper
Life Sciences·Dec 6The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseasesReviewMechanismsPaper
Cells·Nov 28Acetyltransferase p300 Is a Putative Epidrug Target for Amelioration of Cellular Aging-Related Cardiovascular DiseaseReviewMechanismsPaper
Neurochemical Research·Nov 24Biochemical Alterations in White Matter Tracts of the Aging Mouse Brain Revealed by FTIR Spectroscopy ImagingExperiments in miceMechanismsPaper
Cell Reports·Nov 11Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidationExperiments in cellsLipid and ceramide metabolismPaper
International Journal of Molecular Sciences·Sep 29How Are Epigenetic Modifications Related to Cardiovascular Disease in Older Adults?ReviewHistone modification and chromatin remodelingPaper
Frontiers in Genetics·Aug 24Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a LifetimeReviewExercisePaper
Journal of Applied Toxicology·Aug 17Aluminium in cosmetics and personal care productsReviewPopulationsPaper
PLOS One·Aug 12Identification of conserved transcriptome features between humans and Drosophila in the aging brain utilizing machine learning on combined data from the NIH Sequence Read ArchiveComputational studyBiomarkersPaper
Nutrients·Jul 3A Comparison of Gene Expression Profiles of Rat Tissues after Mild and Short-Term Calorie RestrictionsExperiments in ratsDietary restrictionPaper
Frontiers in Aging Neuroscience·Mar 19Cellular Senescence in Brain AgingReviewCellular senescencePaper
Frontiers in Neuroscience·Feb 12Cellular Senescence Triggers Altered Circadian Clocks With a Prolonged Period and Delayed PhasesExperiments in cellsCellular senescencePaper
Hepatology Research·Dec 31Chemical conversion of aged hepatocytes into bipotent liver progenitor cellsExperiments in rat cellsInterventionsPaper
Genetics·Dec 4Starvation Responses Throughout the Caenorhabditiselegans Life CycleReviewMechanismsPaper
Frontiers in Pharmacology·Oct 6Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 AxisCross-sectional study in peopleTelomerase and telomere maintenancePaper
Nature Communications·Sep 27Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restrictionExperiments in model organismsp38 MAPK signalingPaper
Scientific Reports·Sep 18Age-dependent decline in stress response capacity revealed by proteins dynamics analysisExperiments in yeastMechanismsPaper
Endocrinology·Jul 12The Immp2l Mutation Causes Ovarian Aging Through ROS-Wnt/β-Catenin-Estrogen Pathway: Preventive Effect of MelatoninExperiments in miceMelatoninPaper
bioRxiv·Jun 27The genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistancePreprint: experiments in cellsMechanismsPaper
GeroScience·May 13Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopeniaExperiments in miceLipid and ceramide metabolismPaper