Papers on altered gene expression

169 papers3 new in 30 days

Wednesday, April 29

medRxivApr 29

Integrated analysis of bulk multi omic and single-cell sequencing data confirms the molecular origin of hemodynamic changes in Covid-19 infection explaining coagulopathy and higher geriatric mortality

Preprint: computational studyMechanisms

Paper

Friday, April 10

CellsApr 10

Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

Non-randomized trial in 25 peopleResistance training

Paper

Thursday, March 12

AgingMar 12

Survey of senescent cell markers with age in human tissues

Cross-sectional study in peopleCellular senescence

Paper

Saturday, February 1

Conditioning MedicineFeb 1

Molecular Mechanisms of Intermittent Fasting-induced Ischemic Tolerance

ReviewIntermittent fasting

Paper

Tuesday, January 7

Aging CellJan 7

Intrinsically altered lung-resident γδT cells control lung melanoma by producing interleukin-17A in the elderly

Experiments in miceLung

Paper

Wednesday, December 4

Journal of AnatomyDec 4

Age-related changes of tendon fibril micro-morphology and gene expression

Experiments in horsesMechanisms

Paper

Wednesday, October 9

Epigenetics & ChromatinOct 9

Early-life DNA methylation profiles are indicative of age-related transcriptome changes

Experiments in miceDNA methylation

Paper

Saturday, August 10

AgingAug 10

Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome

Cross-sectional study of 52 peopleMechanisms

Paper

Saturday, July 6

Biochemical and Biophysical Research CommunicationsJul 6

Alterations of estradiol-induced histone H3 acetylation in the preoptic area and anteroventral periventricular nucleus of middle-aged female rats

Experiments in ratsMechanisms

Paper

Sunday, June 30

Nursing OutlookJun 30

Patterns of DNA methylation as an indicator of biological aging: State of the science and future directions in precision health promotion

ReviewBiomarkers

Paper

Wednesday, June 12

Neurobiology of Learning and MemoryJun 12

Transcriptomic changes in the prefrontal cortex of rats as a function of age and cognitive engagement

Experiments in ratsMechanisms

Paper

Wednesday, June 5

NutrientsJun 5

Slowing Down Ageing: The Role of Nutrients and Microbiota in Modulation of the Epigenome

ReviewInterventions

Paper

Monday, April 29

ChromosomaApr 29

Epigenetic changes in mammalian gametes throughout their lifetime: the four seasons metaphor

ReviewMechanisms

Paper

Saturday, March 30

Biochemical and Biophysical Research CommunicationsMar 30

Tenomodulin regulates matrix remodeling of mouse tendon stem/progenitor cells in an ex vivo collagen I gel model

Experiments in mouse cellsExtracellular matrix remodeling

Paper

Friday, January 25

JCI InsightJan 25

Epithelial innate immunity mediates tubular cell senescence after kidney injury

Experiments in miceCellular senescence

Paper

Friday, November 16

Scientific ReportsNov 16

Radiation-induced premature cellular senescence involved in glomerular diseases in rats

Experiments in ratsCellular senescence

Paper

Thursday, September 27

Molecular Human ReproductionSep 27

Age-related gene expression profiles of immature human oocytes

Cross-sectional study of 38 peopleMechanisms

Paper

Current Aging ScienceSep 27

Altered Gene Expression of Muscle Satellite Cells Contributes to Agerelated Sarcopenia in Mice

Computational studyMuscle

Paper

Thursday, September 6

Genome BiologySep 6

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

Experiments in miceChromatin and 3D genome organization

Paper

Tuesday, August 21

AgingAug 21

The long non-coding RNA FLJ46906 binds to the transcription factors NF-κB and AP-1 and regulates expression of aging-associated genes

Experiments in cellsMechanisms

Paper

Saturday, July 14

Aging CellJul 14

Proper splicing contributes to visual function in the aging Drosophila eye

Experiments in fliesRNA splicing

Paper

Wednesday, July 11

Insect Molecular BiologyJul 11

Hypoxia adaptation in termites: hypoxic conditions enhance survival and reproductive activity in royals

Experiments in model organismsMechanisms

Paper

Saturday, June 23

GeroScienceJun 23

Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts

Experiments in human cellsmTOR signaling

Paper

Wednesday, May 9

Experimental GerontologyMay 9

Altered gene expression pattern indicates the differential regulation of the immune response system as an important factor in cardiac aging

Experiments in miceImmune response

Paper

Sunday, March 25

Aging CellMar 25

Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction

Experiments in miceDietary restriction

Paper

Friday, October 27

Cellular Physiology and BiochemistryOct 27

Transient Congenital Hypothyroidism Alters Gene Expression of Glucose Transporters and Impairs Glucose Sensing Apparatus in Young and Aged Offspring Rats

Experiments in 6 ratsMechanisms

Paper

Friday, October 13

Biology of ReproductionOct 13

Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium

Cross-sectional study of 9 peopleMechanisms

Paper

Tuesday, June 20

Physiological GenomicsJun 20

Microarray analysis of aging-associated immune system alterations in the rostral ventrolateral medulla of F344 rats

Experiments in ratsImmune response

Paper

Saturday, June 10

Aging CellJun 10

Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape

Experiments in human cellsProgeria

Paper

Saturday, May 27

BMC GenomicsMay 27

Long-lasting effect of obesity on skeletal muscle transcriptome

Experiments in 6 monkeysObesity

Paper