3 papers3 findings
Walking
downin humans1
Walking decreases alpha diversity in humans.
“the intervention group experienced decreased alpha diversity as characterized by Shannon, Richness, and Faith's diversity indices by intervention week 8 (P<0.05).”
Human trialprediabetes and overweight/obesity8 weeksn = 77
Diabetes, obesity, and cardiometabolic CARE16 Mar 2026
Icariin
upin mice1
Icariin increases alpha diversity in mice (25% greater (p < 0.05)).
“females exhibiting 25% greater α-diversity improvement (Shannon index, p < 0.05)”
Animals100 mg/kg/day15 daysfemales
Sex-Dimorphic Gut Microbiota Modulation by Icariin in Older Mice
GSA 2025 abstract31 Dec 2025
Ketogenic diet
downin humans1
Ketogenic diet decreases alpha diversity in humans.
“KD resulted in a significant reduction of alpha diversity”
Human trialseverely obese prediabetic patients2-week
Diabetes, obesity & metabolism15 Dec 2025
In a prospective study of postmenopausal women, 12 weeks of vaginal estrogen shifted urinary bacterial communities towards those seen in women without tissue thinning or…In a prospective study of postmenopausal women, 12 weeks of vaginal estrogen shifted urinary bacterial communities towards those seen in women without tissue thinning or symptoms.