Aging protein signature

Centenarians are associated with aging protein signature in humans (135 DEPs).

“By comparing the centenarian signature to an independent centenarian proteomics study, we identified 135 DEPs in both studies with identical aging directions”

Humansplasma

Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth-Associated Proteins

Aging cell·1 Feb 2026