ADAMTS5

1 paper

Animals1

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Cartilage26 Aug

Single-Cell Transcriptomic Profiling Reveals Superficial Zone Chondrocytes as a Catabolic and Senescent Focus in Osteoarthritis Cartilage

Computational studyCellular senescence

The American Journal of Sports Medicine27 Jan

Effects of Platelet-Rich Plasma on Chondrocyte Senescence and Knee Osteoarthritis Progression

Experiments in ratsKnee osteoarthritis

Autophagy22 Jan

Lactucopicrin promotes the autophagic degradation of MAP2K4/MKK4 by mediating CCDC50 palmitoylation to alleviate osteoarthritis progression

Experiments in miceOsteoarthritis

International Journal of Molecular Sciences16 Oct

Critical Requirement of Senescence-Associated CCN3 Expression in CD44-Positive Stem Cells for Osteoarthritis Progression

Experiments in miceCellular senescence

Aging Cell11 Jul

Alpha-ketoglutarate ameliorates age-related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF-κB signaling

Experiments in miceBones and joints

Redox Biology10 Mar

The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stress

Experiments in ratsOsteoarthritis