Active microglia/macrophages
1 paper1 finding
- Animals1
Interventions
18-aminoguanine
downin mice1
1 study
8-aminoguanine
downin mice1
8-aminoguanine decreases active microglia/macrophages in mice.
“Moreover, 8-AG showed temporary protective effects in the Rho P23H/+ mouse model of retinitis pigmentosa, reducing active microglia/macrophages.”
AnimalsRho P23H/+ mouse model of retinitis pigmentosaretina
Oral 8-aminoguanine against age-related retinal degeneration
Research square6 May 2024Preprint
Latest
1 in 12 monthsAngiogenesis
Myeloid deficiency of RORα exacerbates lipid dysregulation and laser-induced choroidal neovascularization
Experiments in miceMechanisms
Research Square
Oral 8-aminoguanine against age-related retinal degeneration
Preprint: experiments in ratsEye