Activated T cells

Biomarker

2 papers2 findings

  • Humans1
  • Animals1

Upstream

1

CD38

upin mice1

1 study
  1. CD38 increases activated T cells in mice.

    “and a distinct CD8+ T cell profile, characterized by a decrease in activated T cells.”

    Animalsfollowing lipopolysaccharide challenge

    CD38 promotes LPS-induced innate-like activation and proliferation of CD8⁺ T lymphocytes in aged mice

    Frontiers in aging19 Dec 2025

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Associations

1

HIV proviral DNA

upin humans1

1 study
  1. Activated T cells are associated with HIV proviral DNA in humans.

    “The frequency of intact provirus was positively correlated with activated CD4+ and CD8+ T cells.”

    Humansin older PWH

    Age-Associated Expansion of HIV/SIV Reservoirs in People With HIV and SIV-Infected Macaques

    Aging cell6 Oct 2025

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