CD69+TCM cells

1. CD38 is required for CD69+TCM cells in mice.

   “Wild-type mice displayed a significant expansion of CD69+TCM cells after LPS inoculation, an effect that was absent in CD38-deficient animals.”

   Animalsafter LPS inoculation

   CD38 promotes LPS-induced innate-like activation and proliferation of CD8⁺ T lymphocytes in aged mice

   Frontiers in aging·19 Dec 2025

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