AChE activity

Biomarker

3 papers study it45 more mention it2 findings

See all 48

Animals2
Model organisms1

Interventions

Geraniol

downin rats1

1 study

Geraniol decreases AChE activity in rats.
“Geraniol suppressed acetylcholinesterase (AChE) activity”
AnimalsHFD-fed ratseight weeksmales
Amelioration of Age-Related Multiple Neuronal Impairments and Inflammation in High-Fat Diet-Fed Rats: The Prospective Multitargets of Geraniol
Oxidative medicine and cellular longevityOct 18, 2022

Funding

1 grant since 2019

National Institute on AgingUS$1.1m

Aging in Community Health Clinics: Multimorbidity Patterns among Middle-Aged and Older Adults (ACHES)
National Institute on AgingOregon Health & Science UniversityUS$498.8k2019–2024

Latest

8 papers in 12 months

GerontologyOct 5

Long-Term Acetylcholinesterase Depletion Alters the Levels of Key Synaptic Proteins while Maintaining Neuronal Markers in the Aging Zebrafish (Danio rerio) Brain

Experiments in zebrafishSynapse

Paper

Oxidative Medicine and Cellular LongevityOct 29

Amelioration of Age-Related Multiple Neuronal Impairments and Inflammation in High-Fat Diet-Fed Rats: The Prospective Multitargets of Geraniol

Experiments in 64 ratsInterventions

Paper

Food & FunctionDec 9

Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation

Experiments in fliesInterventions

Paper

Neurochemistry InternationalAug 13

Osthol ameliorates Alzheimer's disease-associated cognitive impairment by targeting the estrogen-cholinergic axis in age-stratified female 3×Tg-AD mice

Experiments in miceCognitive impairment

Paper

Toxicology ReportsJul 2

Kaempferol from Moringa oleifera L. increases longevity and ameliorates efavirenz-induced functional senescence in Drosophila melanogaster

Experiments in fliesInterventions

Paper

Neuromolecular MedicineJun 17

Single-cell Transcriptomics Reveals that the SORBS1/FBXO22/BAG3 Axis Drives Astrocyte Senescence via Calcium Signaling and Affects Alzheimer's Disease-Related Neuronal Damage

Experiments in human cellsCellular senescence

Paper

BiomoleculesMay 4

PFAS Compounds Display Distinct Toxicological Effects in Drosophila melanogaster, Reflected by Reduced Viability and Impaired Neuronal Function

Experiments in fliesMechanisms

Paper

Environmental ToxicologyMay 1

From Exposure to Inheritance: Persistent Microplastic-Induced Neural and Mitochondrial Dysfunction in Subsequent Generations of Drosophila melanogaster

Experiments in fliesOxidative phosphorylation

Paper

Neurochemical ResearchFeb 20

Chaetoglobosin F Attenuates Amyloid-β-Induced Neurotoxicity in Caenorhabditis elegans by Regulating Autophagy and Oxidative Stress Via the Insulin/IGF-1 and p38 MAPK Pathways

Experiments in wormsInterventions

Paper

Current Alzheimer ResearchJan 8

Effect of Ascorbic Acid on the Transgenic Drosophila Expressing Human Aβ-42 in the Neurons

Experiments in fliesVitamin C

Paper

See all 48