Geraniol

  • 1 lab in 2 countries
  • Funder: King Faisal University
  • Animals1

Outcomes

4

PI3K–AKT signalling

upin mice1

1 study
  1. Geraniol activates PI3K–AKT signalling in mice.

    “activating PI3K/Akt were the mechanisms that mediated this effect.”

    Animalsin D-gal-treated micebrain40 mg/kg body wt

    Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

    Aging20 Mar 2024

More on PI3K–AKT signalling

Apoptosis

downin mice1

1 study
  1. Geraniol decreases apoptosis in mice.

    “Further, GNL treatment upregulated Nrf2 and HO-1 to reduce oxidative stress and apoptosis.”

    Animalsin D-gal-treated micebrain40 mg/kg body wt

    Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

    Aging20 Mar 2024

More on Apoptosis

Oxidative stress and ROS signalling

downin mice1

1 study
  1. Geraniol decreases oxidative stress and ROS signalling in mice.

    “Further, GNL treatment upregulated Nrf2 and HO-1 to reduce oxidative stress and apoptosis.”

    Animalsin D-gal-treated micebrain40 mg/kg body wt

    Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

    Aging20 Mar 2024

More on Oxidative stress and ROS signalling

Spatial learning and memory

upin mice1

1 study
  1. Geraniol improves spatial learning and memory in mice.

    “Administration of GNL induced a significant increase in spatial learning and memory with spontaneously altered behavior.”

    Animalsin D-gal-treated micebrain40 mg/kg body wt

    Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model

    Aging20 Mar 2024

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