ACBP/DBI

1. Exercise decreases ACBP/DBI in humans.

   “Exercise-induced improvements in physical performance were associated with reduced circulating ACBP/DBI levels across follow-up in older adults, irrespective of HIV status.”

   Human trialolder adults with and without HIV48 weeksn = 60

   Exercise-induced changes in physical performance and circulating acyl-CoA binding protein/diazepam binding inhibitor (ACBP/DBI) in older adults with and without HIV

   The journals of gerontology. Series A, Biological sciences and medical sciences·22 May 2026

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1. Short Physical Performance Battery decreases ACBP/DBI in humans.

   “Each one-point increase in SPPB score was associated with a 203 ng/mL decrease in plasma ACBP/DBI.”

   Human trialolder adults with and without HIV48 weeksn = 60

   Exercise-induced changes in physical performance and circulating acyl-CoA binding protein/diazepam binding inhibitor (ACBP/DBI) in older adults with and without HIV

   The journals of gerontology. Series A, Biological sciences and medical sciences·22 May 2026

1. Physical function is associated with ACBP/DBI in humans.

   “Over 48 weeks, increases in aerobic endurance and SPPB scores were independently associated with significant reductions in circulating ACBP/DBI levels.”

   Human trialolder adults with and without HIV48 weeksn = 60

   Exercise-induced changes in physical performance and circulating acyl-CoA binding protein/diazepam binding inhibitor (ACBP/DBI) in older adults with and without HIV

   The journals of gerontology. Series A, Biological sciences and medical sciences·22 May 2026

1. Homo sapiens are associated with ACBP/DBI in humans.

   “in humans, ACBP/DBI levels increase in various tissues, as well as in the plasma, in the context of aging”

   Reviewaging, obesity, infection or diseases

   Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint"

   Aging cell·26 Jun 2023

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