Acbp/dbi neutralization

1. Acbp/dbi neutralization induces autophagy in mice.

   “These lifespan and healthspan-extending effects of ACBP/DBI suppression are coupled to the induction of autophagy.”

   Reviewsuppression of ACBP/DBI

   Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint"

   Aging cell·26 Jun 2023

More on Autophagy

1. Acbp/dbi neutralization extends lifespan in mice.

   “as it enhances lifespan or healthspan in yeast, plant leaves, nematodes, and multiple mouse models.”

   Reviewgenetic or antibody-mediated inhibition

   Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint"

   Aging cell·26 Jun 2023