8-Oxo-7,8-dihydro-2'-deoxyguanosine

Biomarker

3 papers2 findings

  • Animals2
  • Cells1

Interventions

1

Caloric restriction

downin rats1−30%

1 study
  1. Caloric restriction decreases 8-Oxo-7,8-dihydro-2'-deoxyguanosine in rats (30%).

    “8-Oxo-7,8-dihydro-2'-deoxyguanosine in skeletal muscle mtDNA was unaffected by aging but decreased 30% with caloric restriction”

    Animalsskeletal muscle

    Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart

    American journal of physiology. Regulatory, integrative and comparative physiology3 Oct 2002

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Upstream

1

birds

downin birds1

1 study
  1. birds decrease 8-Oxo-7,8-dihydro-2'-deoxyguanosine in birds.

    “Lower steady-state 8-oxodG values were observed in all cases in the heart mtDNA in birds than in mammals.”

    Animalsheart

    8-oxo-deoxyguanosine levels in heart and brain mitochondrial and nuclear DNA of two mammals and three birds in relation to their different rates of aging

    Aging (Milan, Italy)1 Oct 1999

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