[18F]flortaucipir PET SUVr

Male sex decreases [18F]flortaucipir PET SUVr in humans (β=-0.10, p=0.007).

“and lower Tau‐PET SUVr (β=‐0.34, p <0.001 and β=‐0.10, p = 0.007)”

Humansamyloid-positive MCI or dementian = 680

Lower Antemortem [ ¹⁸ F]flortaucipir PET retention in Males and Older Individuals is Explained by Lower Postmortem Tau Tangle Density

AAIC 2025 abstract·23 Dec 2025

Older age decreases [18F]flortaucipir PET SUVr in humans (β=-0.34, p<0.001).

“older age and male sex were associated with a lower prevalence of Tau‐PET‐positivity (β=‐0.44, p <0.001 and β=‐0.43, p = 0.02 respectively) and lower Tau‐PET SUVr (β=‐0.34, p <0.001”

Humansamyloid-positive MCI or dementian = 680

Lower Antemortem [ ¹⁸ F]flortaucipir PET retention in Males and Older Individuals is Explained by Lower Postmortem Tau Tangle Density

AAIC 2025 abstract·23 Dec 2025