Spencer Flynn
Harvard University2 papersOpenAlex
Papers
JACC AdvancesHumans
Body fat and inflammation link ultraprocessed food to heart risk
In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident…In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident cardiovascular disease.
medRxivHumansPreprint
ASXL1 mutations in clonal hematopoiesis accelerate aortic valve calcification
Large human cohort data and cell experiments show that ASXL1-driven clonal hematopoiesis worsens aortic valve hemodynamics and promotes calcification…Large human cohort data and cell experiments show that ASXL1-driven clonal hematopoiesis worsens aortic valve hemodynamics and promotes calcification through inflammatory signaling.