Stéphanie Debette

Centre National de la Recherche Scientifique2 papersORCID 0000-0001-8675-7968OpenAlex

Papers

medRxivHumansPreprint2 Oct

Dementia polygenic risk tracks disability and death

Compared to favorable profiles, poor dementia polygenic scores carried higher risk of dementia, disability, or death (HR 1.43, 95% CI 1.26–1.63).Compared to favorable profiles, poor dementia polygenic scores carried higher risk of dementia, disability, or death (HR 1.43, 95% CI 1.26–1.63).

Neurology GeneticsHumans1 Oct

GLP-1 receptor agonists link to lower stroke and Alzheimer risk

A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.