Mary Pat Reeve

Broad Institute1 paperORCID 0000-0003-1788-2321OpenAlex

Papers

medRxivHumansPreprint

Genetic scores add more predictive power at lower clinical risk

For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with…For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence than those remaining low-risk.