Mary Pat Reeve
Broad Institute1 paperORCID 0000-0003-1788-2321OpenAlex
Papers
medRxivHumansPreprint
Genetic scores add more predictive power at lower clinical risk
For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with…For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence than those remaining low-risk.