Carlos C Cruchaga
Washington University in St. Louis2 papersORCID 0000-0002-0276-2899OpenAlex
Papers
Neurology GeneticsHumans
GLP-1 receptor agonists link to lower stroke and Alzheimer risk
A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.
Nature GeneticsHumans
Germline HRD limits therapy-driven clonal hematopoiesis
Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency…Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.