No phaseCompleted

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV (HEALTH)

Sponsor
University of Colorado, Denver (Academic or other)
Enrolment
118 enrolled
Conditions
Hiv; Fatigue; Mobility Limitation
Interventions
HIIT (intervention); CME (active control); Coaching; Control text message
Ages
adults, older adults
Registry
NCT04550676

From the registry

This is a multi-site, randomized, single-blind (researchers), active treatment concurrent control trial with individuals aged 50-80 living with HIV who experience fatigue and live a sedentary lifestyle. The overall goals of this proposal are to determine whether high-intensity interval training (HIIT) can overcome physical function impairments and increased fatigue (Aim 1) and impairments in mitochondrial bioenergetics of older people with HIV (PWH) to a greater extent than continuous moderate-intensity exercise (CME) (Aim 2). The investigators further seek to determine whether a biobehavioral coaching intervention following either HIIT or CME can promote long-term adherence to physical activity (Aim 3), a crucial component of the sustainability of the intervention. This study will enroll 100 participants in Aurora, Colorado and Seattle, Washington. Data collection will occur at each visit, with baseline data collected at the initial visit. A 3-month follow-up will be conducted over the phone from the date of the final visit. The initial enrollment goal of 100 was increased to 120…

Primary outcomes

  • Change in Physical Function (Part 1)
Full record on ClinicalTrials.gov

Papers citing this trial