Papers by W. Wang

400+ results

  1. Research Square

    Loss of a matrix enzyme triggers adult bone loss in mice

    Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.

    Preprint: experiments in miceBones and joints
  2. Research Square

    Standard lab tests mislabel normal aging in Chinese adults

    In 4,392 healthy Chinese adults, standard medical reference ranges flagged 58.8% of women aged 50 to 59 as having abnormal cholesterol.In 4,392 healthy Chinese adults, standard medical reference ranges flagged 58.8% of women aged 50 to 59 as having abnormal cholesterol.

    Preprint: cross-sectional study of 4,392 peopleBiomarkers
  1. Preprints.org

    Global study defines seven key symptom areas for menopause

    Data from 5,228 participants and 302 interviews across 13 countries identified seven core physical, mental, and social domains to track during menopause.Data from 5,228 participants and 302 interviews across 13 countries identified seven core physical, mental, and social domains to track during menopause.

    Preprint: study of 5,228 peopleMenopause
  2. Psychiatry Research

    Sleep and muscle problems linked to rising depressive symptoms

    Adults with both problems were linked to rapidly rising rather than persistently low depressive symptoms, with an odds ratio of 4.130.Adults with both problems were linked to rapidly rising rather than persistently low depressive symptoms, with an odds ratio of 4.130.

    Cohort study of 11,295 peopleMuscle
  3. Ecotoxicology and Environmental Safety

    Tributyl phosphate caused signs of liver aging in rats

    An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.

    Experiments in ratsMechanisms
  4. Archives of Gerontology and Geriatrics

    Childhood loneliness linked to faster frailty progression

    Definite childhood loneliness was linked to faster frailty progression than no childhood loneliness, with an estimated difference of 0.289 in the statistical model.Definite childhood loneliness was linked to faster frailty progression than no childhood loneliness, with an estimated difference of 0.289 in the statistical model.

    Cohort study of 13,643 peoplePopulations
  5. Research Square

    Family support linked to daily tasks in adults aged 45–85 in China

    In 12,769 adults in China, increasing financial reciprocity with minimal interaction was linked to 0.67 points higher daily task limitation scores than high exchange with…In 12,769 adults in China, increasing financial reciprocity with minimal interaction was linked to 0.67 points higher daily task limitation scores than high exchange with stable interaction.

    Preprint: cohort study of 12,769 peoplePopulations
  6. medRxiv

    Polygenic risk links to disease burden and hospital use in Taiwan

    In a preprint, top-decile integrated genetic risk was linked to 23.9% more hospital days, and elevated diabetes risk corresponded to 1.50 lost healthy life-years.In a preprint, top-decile integrated genetic risk was linked to 23.9% more hospital days, and elevated diabetes risk corresponded to 1.50 lost healthy life-years.

    Preprint: cohort study in peoplePopulations
  7. medRxiv

    Brainstem MRI signal links to an Alzheimer's marker in adults

    Each standard deviation decrease in locus coeruleus intensity was associated with 53% higher odds of testing positive for an Alzheimer's blood marker.Each standard deviation decrease in locus coeruleus intensity was associated with 53% higher odds of testing positive for an Alzheimer's blood marker.

    Preprint: cohort study of 163 peopleAlzheimer's disease