Humans57,888 matched adults5 yearsCohort study
Loneliness and all-cause mortality in the United States

PLOS One
Abstract
Importance Loneliness affects more than half of US adults and has been declared a public health epidemic, yet whether clinically documented loneliness independently predicts mortality across diverse populations remains unclear.
The paper
Oluwasegun Austine Akinyemi, Oluebubechukwu Eze, Mojisola Fasokun, Temitope Ogundare
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Ifeoma Mba-Madubuike, Temitayo Ogundipe, Delia Singleton, Ayomide Ogunsakin, Samar Khalil, K. Gordon, Miriam B Michael, Kakra Hughes,Howard University · Columbia University Irving Medical Center
PLOS One · 25 Sep 2026 · CC BY