NAD⁺ Metabolic Reprogramming Drives CD8⁺ T Cells Senescence and Exacerbates Ulcerative Colitis

More on Cellular senescence

• A distinct p21-driven macrophage senotype accumulates during aging and liver disease

  bioRxiv · 2 Oct 2026

• Macrophage CD38 drives age-related placental senescence by depleting NAD+

  Nature Communications · 2 Oct 2026

• Nicotinamide riboside improves parasite control in mice

  bioRxiv · 5 Oct 2026

  

• Mitochondrial TFAM limits CD8+ T cell lung damage in mice

  bioRxiv · 2 Oct 2026