Skip to content
A
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
MechanismsAnimals

Adaptive oncogenesis of β-catenin emerges from declining liver tissue integrity

Nature Communications

  • CTNNB1
  • ER unfolded protein response
  • NRF2–KEAP1 antioxidant response
  • Hepatocellular carcinoma
  • Tumorigenesis
  • Mice

The paper

Illendula A, Hewett CK, Hayata Y et al.

Nature Communications · 10 Aug 2026

doi.org/10.1038/s41467-026-76373-yPubMed 42706261

More on PI3K–AKT signalling

  • Deleting beta-catenin in mouse disc cells lowers inflammation and immune cell recruitment

    Aging Cell · 2 Oct 2026

  • A distinct p21-driven macrophage senotype accumulates during aging and liver disease

    bioRxiv · 2 Oct 2026

  • Blind mole-rat mesenchymal stem cells resist carcinogen-induced damage through preserved p53 signaling

    Stem Cells · 3 Oct 2026

  • DNA damage differed by sex in mice with impaired DNA repair

    Research Square · 7 Oct 2026

© 2026 AgingResearch.News

PrivacyTermsContact

    News

    See all →

    Study links stable gene regulation to longevity in a 194-year-old giant tortoise

    ResearchPhys.org and 1 more

    Longevica finds over sixty life-extending compounds in four-year mouse screen

    CompanyLongevity.Technology

    Immune aging accelerates near ages 40 and 60

    ResearchFuturity

    Trials

    See all →

    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered7 Oct 2026

    AI-Based Conversational Social Support for Older Adults With Heart Failure

    Chang Gung University of Science and Technology

    Trending

    Evidence →
    1. Intervention · 66 papersExercise
    2. Gene · 24 papersAPOE
    3. Disease · 125 papersCardiovascular disease
    4. Process · 120 papersInflammation
    5. Biomarker · 46 papersBody mass index
    6. Intervention · 44 papersSmoking

    Topics

    See all →
    • Mechanisms293
    • Interventions412
    • Biomarkers387
    • Populations562
    • AI & data144
    • Industry & policy28
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News