Skip to content
A
  • HomeHome
  • SearchSearch
  • AskAsk
  • SavedSaved
InterventionsAnimals

Targeting cellular senescence mitigates chemotherapy-induced bone loss in young and aged mice

GeroScience

  • Dasatinib + quercetin
  • Cellular senescence
  • Extracellular matrix remodelling
  • Osteoporosis
  • Marrow adiposity
  • Mice

The paper

Izquierdo DJ, Blancarte-Hernandez E, Schurman CA et al.

GeroScience · 2 Sep 2026

doi.org/10.1007/s11357-026-02485-4PubMed 42686970

More on Cellular senescence

  • Lactate receptor activation reduces arterial senescence in mice

    bioRxiv · 2 Oct 2026

  • Senescent prostate cancer cells drive stromal remodeling through TGF-beta signaling

    Neoplasia · 2 Oct 2026

  • Osteoporosis therapies affect bone cell spaces differently in mice

    bioRxiv · 6 Oct 2026

  • Chronic stress worsened bone loss in mice after ovary removal

    Journal of Cellular Biochemistry · 6 Oct 2026

  • News
  • Trials
  • Topics
  • Evidence
  • Conferences
  • Stats
  • Updates
  • API
  • Plus

© 2026 AgingResearch.News

PrivacyTermsContact

    News

    See all →

    Direct AMPK activation modestly lengthens lifespan in short-lived species

    ResearchFight Aging!

    A protein complex with a bound molecule sits beside an unbound complex, with slightly more intact cells beneath the bound form and more fragments beneath the…

    Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

    ResearchNature Aging and 1 more

    Senescence-inhibiting isoform Δ133p53α slows premature aging in mice

    Researchnpj Aging

    Figure 1

    Trials

    See all →

    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered7 Oct 2026

    AI-Based Conversational Social Support for Older Adults With Heart Failure

    Chang Gung University of Science and Technology

    Trending

    Evidence →
    1. Intervention · 64 papersExercise
    2. Gene · 22 papersAPOE
    3. Disease · 122 papersCardiovascular disease
    4. Process · 117 papersInflammation
    5. Biomarker · 43 papersBody mass index
    6. Intervention · 42 papersGLP-1 receptor agonists

    Topics

    See all →
    • Mechanisms293
    • Interventions412
    • Biomarkers387
    • Populations561
    • AI & data141
    • Industry & policy28
    • Conferences
    • Stats
    • Updates
    • API
    • Plus
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News